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Prescription Cessation Medications

You don’t have to quit cold turkey — you have options when it comes to making your quit stick. Talk to your health care provider about prescription medications like bupropion (generic Zyban) or varenicline (generic Chantix).

Get Extra Support for Your Quit

Prescription medications like bupropion or varenicline (generic Chantix) are valuable tools for those with severe nicotine dependence. Quitting can be hard, but you don’t have to do it without help. Using a medication to assist you on your quit can make all the difference and improves your chances of staying quit. Do your own research, then ask your health care provider if a prescription medication may be right for you.

Contact the QuitLine
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DID YOU KNOW? When you enroll in the South Dakota QuitLine’s coaching program, not only are you two times more likely to successfully quit, but you also may be eligible to receive prescription medication for free* as a result.

With a Prescription

Varenicline (Brand Name: Chantix)

Varenicline is a great option for those who have tried using other cessation medications in the past but have yet to quit successfully. It is used solely to help people stop using tobacco. Here’s what you need to know about varenicline. If you have further questions, contact your health care provider to find out if varenicline is the right option for you.

Varenicline greatly increases your likelihood of quitting for good with a single medication.

  • What is it?
  • How can I get it?
  • How does it work?
  • What are the possible side effects?

Varenicline, also known as Chantix, is a nicotine-free pill that has been effective for many quitters, prescribed by your provider. The medication acts on nicotine receptors in the brain, blocking your cravings and reducing symptoms of withdrawal.

Visit your health care provider to find out if varenicline is right for you. When you enroll in the South Dakota QuitLine coaching program, you may be eligible to get your prescription at no cost.

Tell your doctor or other health care provider:

  • About your willingness to quit.
  • If you’ve attempted to quit in the past.
  • What methods you may have used to attempt quitting.
  • If you have used the SD QuitLine or that you’d like to start.

Once you’ve been prescribed varenicline, you will be instructed to start the medication about a week before your official quit date. You will be on the medication for about 12 weeks, unless your health care provider advises you otherwise. Your health care provider will provide you with further details.

Note: Varenicline should not be taken with NRT or any other cessation medication.

All medications have side effects. When taking varenicline, about 10 percent of people will experience side effects — most are insignificant.

  • Constipation
  • Gas
  • Vomiting
  • Nausea
  • Changes in taste
  • Strange dreams or sleep patterns
  • Mood or behavior changes

If you have trouble with any of these side effects, ask your health care provider about reducing your dosage.

With a Prescription

Bupropion (Brand Name: Zyban, Wellbutrin, Aplenzin)

Bupropion may be a good choice for those who have tried using other cessation medications in the past but have yet to quit successfully. While bupropion is used to help people quit tobacco, it is also prescribed for other conditions. Here’s what you need to know about bupropion. If you have further questions, contact your health care provider to find out if bupropion is the right option for you.

What is it?

Bupropion is a nicotine-free, antidepressant pill that a health care provider can prescribe to you. This twice-a-day medication helps by reducing symptoms of withdrawal.

How can I get it?

Visit your health care provider to find out if bupropion is right for you. When you enroll in the South Dakota QuitLine coaching program and secure a prescription from your health care provider, you may be eligible to get your prescription at no cost.

How does it work?

Since bupropion is an antidepressant, it reduces urges and withdrawal symptoms by acting on the chemicals in your brain that are linked to cravings. Once prescribed, take bupropion one to two weeks before your quit date or follow your health care providers instructions. Use for about 12 weeks.

Note: Bupropion can be combined with NRT.

What are the possible side effects?
  • Dry mouth
  • Skin rash
  • Trouble sleeping
  • Shakiness
  • Anxiety
  • Seizures

If you develop hives, trouble breathing or another sign of allergic reaction, stop use immediately and call your health care provider.

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*Receiving a free prescription of varenicline or bupropion requires a prescription from a provider, which may include an office visit charge or copay, depending on insurance status. The medication itself can be offered at no charge when a patient enrolls in phone coaching with the South Dakota QuitLine.